MIAplex® was developed for the rapid and multiparametric detection and quantification of proteins, viruses, toxins or bacteria in biological samples. The system incorporates the use of a set of magnetic beads differing by their magnetic properties.
In MIAplex®, specific antibodies (or DNA probes) are coupled with a unique magnetic bead which can be identified by its characteristic magnetic signature.
With a single multi-coil reading head, each unique magnetic bead can be identified within the same lateral flow test line. The reader is able to discriminate each magnetic signature and no spatial resolution is required to identify and quantify multiple targets in one test.
| The combined signal is resolved through data processing to discretely identify and quantify each unique magnetic bead signature, thus the amount of each analyte in the sample. |
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A large variety of magnetic materials and compositions are candidates for multiparametric magnetic immunoassays.
